THC-(S)-Mephenytoin CSV JSON

In Vitro Enzyme Inhibition Experiment

THC-(S)-Mephenytoin

Inhibition was detected.  Cutoff used — Not specified

mephenytoin, (s)-

4-hydroxymephenytoin, (s)-

  • CYP2C19 4311137

Recombinant expression system Baculovirus-insect cells
Cytochrome B5 Not available

Results

% inhibition at 10 μM estimated from Fig 2D.
IC50 (Table 2).
Ki (Table 3)

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

Commercially available

250 μL

40 min

NADPH regenerating system

5 min

No NADPH with precipitant