CBD-(S)-Mephenytoin CSV JSON

In Vitro Enzyme Inhibition Experiment

CBD-(S)-Mephenytoin

Inhibition was detected.  Cutoff used — Not specified

mephenytoin, (s)-

cannabidiol (cbd)

4-hydroxymephenytoin, (s)-

  • CYP2C19 4311137

Recombinant expression system Baculovirus-insect cells
Cytochrome B5 Not available

Results

%inhibition at 10 μM of CBD (Fig. 1)
IC50 (Table 1), Ki (Table 3)

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Commercially available

250 μL

40 min

NADPH regenerating system

5 min

No NADPH with precipitant