Experiment #NPDI-sYa6vQ CSV JSON

In Vitro Enzyme Induction Experiment

Induction was detected.  Cutoff used — Not specified

mitragynine

  • CYP3A4 4306811

Cell system HepG2 cell line

Figure 3

Results

The protein expression of CYP3A4 was slightly induced after treatment with mitragynine, with higher relative protein expression at concentrations of 0.1uM and above, with the highest induction occurring at 0.5 uM relative to untreated controls

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

Protein expression

0.1, 0.5, 1, 5, 10, 25 uM

48 hours

Control Experiment