[{"id":148,"uid":"NPDI-vQCHYg","name":"Characterization of Kratom material","napdiIdentifier":"cb_14","overallSummary":null,"pubmedId":null,"embaseId":null,"croIdentifier":"UNCG","croInformation":"UNCG","dateStart":null,"dateEnd":null,"internalComment":null,"status":"published","compoundId":null,"naturalProductUid":"NP-00ed1235-cbd8-4117-85df-298b8b3cdcad","naturalProductSampleId":null,"studySourceTypeId":3,"naturalProduct":{"uid":"NP-00ed1235-cbd8-4117-85df-298b8b3cdcad","binomial":"Mitragyna speciosa","name":"Kratom","itis":null,"srs":"d469b67d-e9a6-459f-b209-c59451936336","source_id":"","conceptId":null},"compound":null,"studySourceType":{"id":3,"name":"Unpublished data submitted through a NaPDI form"},"experiments":[{"id":723,"uid":"NPDI-XuAtuQ","name":"Characterization of Kratom material","overallEffect":0,"isControlData":false,"isIc50Shift":false,"croCutoff":null,"croIdentifier":null,"comment":"<p><strong>Comparison with Literature:</strong><br />A recent report [1] found that depending on source material, mitragyninewas detected in kratom (<em>M. speciosa</em>) products at a concentration range between 1 and 6% of leaf content (10 to 60 mg/g) and that 7-hydroxymitragynine levels ranged from 0.01 to 0.04% (0.1 to 0.4 mg/g).&nbsp; Thus, the reported values we have provided are consistent with literature precedent. <br />Kikura-Hanajiri, R., Kawamura, M., Maruyama, T. et al. Forensic Toxicol(2009) 27: 67. https://doi.org/10.1007/s11419-009-0070-52</p>","experimentalConditionsComment":null,"resultsComment":null,"internalComment":null,"objectCompoundId":null,"objectMetaboliteCompoundId":null,"precipitantCompoundId":null,"cytochromeB5Id":null,"studyId":148,"experimentTypeId":10,"testSystemId":null,"ic50ShiftExperimentId":null,"controlDataExperimentId":null,"controlDataForExperimentId":null,"naturalProductSampleId":"NPS-oDLatA","experimentType":{"id":10,"name":"Characterization of Material","isInVitro":false,"isTransporter":false,"isEnzyme":false,"purl":"http://purl.obolibrary.org/obo/DIDEO_00005004"},"objectCompound":null,"precipitantCompound":null,"objectMetaboliteCompound":null,"enzymes":[],"transporters":[],"quantifiedMetabolites":[{"id":247,"name":"rotundifoline","unii":null,"inChIKey":"IXWWTVSMMIIIFZ-LWWKTLCYSA-N","publicDescription":null,"internalComment":null,"conceptId":null,"enantiomerOfId":null,"experiment_quantified_metabol":723},{"id":104,"name":"7-hydroxymitragynine","unii":null,"inChIKey":"RYENLSMHLCNXJT-CYXFISRXSA-N","publicDescription":null,"internalComment":null,"conceptId":null,"enantiomerOfId":null,"experiment_quantified_metabol":723},{"id":94,"name":"mitragynine","unii":null,"inChIKey":"LELBFTMXCIIKKX-QVRQZEMUSA-N","publicDescription":null,"internalComment":null,"conceptId":null,"enantiomerOfId":null,"experiment_quantified_metabol":723}]}]}]