In Vitro Enzyme Inhibition Experiment

2C8 Inhibition by Aq GS Extract

Negligible Inhibition was detected.  Cutoff used — not specified


6-alpha-hydroxy paclitaxel

  • CYP2C8 4306333

Cell fraction Pooled human liver microsomes -7999662


Fig 1 Estimate at 20 μM

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

In-house preparation

HHM-247 and HHM-258

15 min


10 min

No NADPH with precipitant

1 or 20 μM