In Vitro Enzyme Inhibition Experiment
Screening of kratom extracts as inhibitors of CYP3A activity in HLM
Inhibition was detected. Cutoff used —
50% inhibition at the highest tested concentration
Cell fraction Pooled human liver microsomes -7999662
Three methanolic Kratom extracts were tested, K-50, K-51 and K-52.
|Sample||Compound measured||Value||Measurement||Study sequence||Additional information||N replicates|
2, 10, and 20 µg/ml