Lopinavir P-gp Inhibition CSV JSON

In Vitro Transporter Kinetics Experiment

Lopinavir P-gp Inhibition

Transport Activity was detected.  Cutoff used — Not specified

berberine 19012197

  • P-gp (ABCB1)

Transfected / siRNA knock-out / injected cells MDCK transfected cells


Figure 5b - reported value above is for 25 μM of lopinavir vs control and is significant p< 0.05

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Concentration of HIV PI's were 5, 15, and 25 μM

Cell Culture Conditions


Assay Conditions

4 h

37 deg C

5 μM