- Natural product: Cannabis (Cannabis sativa)
- Associated study: Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes
In Vitro Enzyme Inhibition Experiment
Weak Inhibition of 8-beta-hydroxylation of delta-9-THC by sulfaphenazole
Negligible Inhibition was detected. Cutoff used —
Not provided
- CYP2C
Cell fraction Pooled human liver microsomes -7999662
Results
Table 1
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates | 
|---|
Experimental Conditions
10 microG
                                                            
                                                                Commercially available
                                                                
                                                                
                                                            
                                                        
20 min
                                                            
                                                                NADPH
                                                                
                                                                
                                                            
                                                                NADPH regenerating system
                                                                
                                                                
                                                            
                                                        
64 µM
50 µM
