Inhibition of 11-hydroxylation of delta-9-THC by sulfaphenazole CSV JSON

In Vitro Enzyme Inhibition Experiment

Inhibition of 11-hydroxylation of delta-9-THC by sulfaphenazole

Inhibition was detected.  Cutoff used —

Not provided

sulfaphenazole

11-hydroxy-delta-9-tetrahydrocannabinol

  • CYP2C

Cell fraction Pooled human liver microsomes -7999662

Results

Table 1

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

10 microG

Commercially available

20 min

NADPH
NADPH regenerating system

64 µM

50 µM