- Natural product: Licorice (Glycyrrhiza glabra)
- Associated study: Cytochrome P450 inhibition by licorice species Glycyrrhiza glabra L. and fourteen licorice constituents
In Vitro Enzyme Inhibition Experiment
Negligible inhibition of CYP2A6 by G. glabra Licorice extract
Negligible Inhibition was detected. Cutoff used —
> 100 µg/ml
- CYP2A6 4309826
Cell fraction Pooled human liver microsomes -7999662
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
0.2 mg/mL
10 min
NADPH
1.5 µM
11 concentrations from 0.005–250 μg/mL