In Vitro Enzyme Inhibition Experiment

Inhibition of UGT by (-)-Epigallocatechin Gallate (IC50 Determination)

Inhibition was detected.  Cutoff used — Not provided

4-methylumbelliferone

4-methylumbelliferone glucuronide

  • UGT

Cell fraction Individual human intestinal microsomes -7999704

Results

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

Bovine serum albumin (0.05%) was added into the incubation system.

0.2 mg/mL

Commercially available

1410074

UDPGA

Not available

Not available

100 µM

3.9-600 µM