- Natural product: Green tea (Camellia sinensis)
- Associated study: Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation
In Vitro Enzyme Inhibition Experiment
Inhibition of UGT by (-)-Epigallocatechin Gallate (IC50 Determination)
Inhibition was detected. Cutoff used — Not provided
- UGT
Cell fraction Individual human intestinal microsomes -7999704
Results
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
---|
Experimental Conditions
Bovine serum albumin (0.05%) was added into the incubation system.
0.2 mg/mL
Commercially available
1410074
UDPGA
Not available
Not available
100 µM
3.9-600 µM