Black pepper - In Vitro Nuclear Receptor Induction PXR Experiment - 3 CSV JSON

In Vitro Nuclear Receptor Induction Experiment

Black pepper - In Vitro Nuclear Receptor Induction PXR Experiment - 3

Induction was detected.  Cutoff used —

An activation of 2-folds or higher. 

black pepper extract

  • Pregnane X receptor (PXR)

Cell system PXR-transfected hepatic cells

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Luciferase activity (Reporter gene assay)

50,000 cells/well in 96-well plates

No

6.7 µg/mL

24 hrs for PXR induction