N-methylcytisine - Effect of Sophora Flavescens and N-Methylcytisine on CYP3A4 in HepaRG Cells Experiment - 1 CSV JSON
- Natural product: Shrubby sophora (Sophora flavescens)
- Associated study: Chinese Herbal Medicine Sophora Flavescens Activates PXR
In Vitro Nuclear Receptor Induction Experiment
N-methylcytisine - Effect of Sophora Flavescens and N-Methylcytisine on CYP3A4 in HepaRG Cells Experiment - 1
Induction was detected. Cutoff used —
> control
- CYP3A4 4306811
Cell system PXR-transfected hepatic cells
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
mRNA expression
2x10^5 cells/ml (100 μl in each well)
10 μM
48 hours