- Natural product: Kratom (Mitragyna speciosa)
- Associated study: The inhibitory effects of mitragynine on P-glycoprotein in vitro
In Vitro Transporter Induction Experiment
Induction of P-gp protein expression by 0.001 µM rifampicin
Induction was detected. Cutoff used —
p < 0.05 compared with control
- P-gp (ABCB1)
Cell system Caco-2 cells
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
Protein expression
0.001 µM
72 h
Western blot