In Vitro Enzyme Kinetics Experiment

THC-COOH-UGT1A3

Metabolism was detected.

glucuronide

  • UGT1A3

Recombinant expression system Baculovirus-insect cells
Cytochrome B5 No

Table 2

Results

Table 2

Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

Metabolite formation study

5 μg

In-house preparation

30 μL

90 min (screening), 30 min (kinetics)

MgCl2

UDPGA