- Natural product: Goatweed (Hypericum perforatum)
- Associated study: St. John's wort mixed parts extract Nuclear Receptor Induction study - Ole Miss
In Vitro Nuclear Receptor Induction Experiment
St. John's wort - In Vitro Nuclear Receptor Induction PXR Experiment - 2
Induction was detected. Cutoff used —
An activation of 2-folds or higher.
- Pregnane X receptor (PXR)
Cell system PXR-transfected hepatic cells
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
Luciferase activity (Reporter gene assay)
50,000 cells/well in 96-well plates
No
20 µg/mL
24 hrs for PXR induction