- Natural product: Garcinia (Garcinia gummi)
- Associated study: Garcinia cambogia fruit extract Nuclear Receptor Induction study - Ole Miss
In Vitro Nuclear Receptor Induction Experiment
Garcinia cambogia - In Vitro Nuclear Receptor Induction PXR Experiment - 3
Non-induction was detected. Cutoff used —
An activation of 2-folds or higher.
- Pregnane X receptor (PXR)
Cell system PXR-transfected hepatic cells
Results
Sample | Compound measured | Value | Measurement | Additional information | N replicates |
---|---|---|---|---|---|
garcinia extract | 1.27 ± 0.20-fold | Change from vehicle control Mean ± SD (arithmetic) | P-value: Not calculated | 2 |
Experimental Conditions
Luciferase activity (Reporter gene assay)
50,000 cells/well in 96-well plates
No
6.7 µg/mL
24 hrs for PXR induction