- Natural product: Licorice (Glycyrrhiza glabra)
- Associated study: Licorice root extract Nuclear Receptor Induction study - Ole Miss
In Vitro Nuclear Receptor Induction Experiment
Licorice - In Vitro Nuclear Receptor Induction PXR Experiment - 1
Induction was detected. Cutoff used —
An activation of 2-folds or higher.
- Pregnane X receptor (PXR)
Cell system PXR-transfected hepatic cells
Results
| Sample | Compound measured | Value | Measurement | Additional information | N replicates |
|---|---|---|---|---|---|
| licorice extract | 2 ± 0.03-fold | Change from vehicle control Mean ± SD (arithmetic) | P-value: Not calculated | 2 |
Experimental Conditions
Luciferase activity (Reporter gene assay)
50,000 cells/well in 96-well plates
No
60 µg/mL
24 hrs for PXR induction