Weak Inhibition of Speciociliatine for CYP2D6 CSV JSON

In Vitro Enzyme Inhibition Experiment

Weak Inhibition of Speciociliatine for CYP2D6

Negligible Inhibition was detected.  Cutoff used —

IC50 = 45 μM

dextromethorphan 1119510

speciociliatine

dextrorphan 4349487

  • CYP2D6 4173631

Cell fraction Pooled human liver microsomes -7999662

Results

% result estimated from Figure S2 at around 100 µM

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.1 mg/ml

200 µL

15 min

NADPH

7 µM

0 - 100 µM

Control Experiment