- Natural product: Licorice (Glycyrrhiza glabra)
- Associated study: Cytochrome P450 inhibition by licorice species Glycyrrhiza glabra L. and fourteen licorice constituents
In Vitro Enzyme Inhibition Experiment
Inhibition of CYP1A2 by G. glabra Licorice extract
Inhibition was detected. Cutoff used —
>100 µg/ml
- CYP1A2 4312402
Cell fraction Pooled human liver microsomes -7999662
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
0.2 mg/mL
10 min
NADPH
100 µM
11 concentrations from 0.005–250 μg/mL