Negligible Inhibition of CYP2D6 by G. uralensis Licorice extract CSV JSON

In Vitro Enzyme Inhibition Experiment

Negligible Inhibition of CYP2D6 by G. uralensis Licorice extract

Negligible Inhibition was detected.  Cutoff used —

> 100 µg/ml

dextromethorphan 1119510

ethanolic extract of licorice g. uralensis

dextrorphan 4349487

  • CYP2D6 4173631

Cell fraction Pooled human liver microsomes -7999662

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.2 mg/mL

10 min

NADPH

2.5 µM

11 concentrations from 0.005–250 μg/mL