- Natural product: Shrubby sophora (Sophora flavescens)
- Associated study: Chinese Herbal Medicine Sophora Flavescens Activates PXR
In Vitro Nuclear Receptor Induction Experiment
Sophora Flavescens - Effect on PXR Activation in DPX2 Cells Experiment - 1
Induction was detected. Cutoff used —
≥ positive controls (Schisandrae chinensis Baill and Glycyrrhizae uralensis Fisch)
- Pregnane X receptor (PXR)
Cell system PXR-transfected hepatic cells
Results
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
---|
Experimental Conditions
Luciferase activity (Reporter gene assay)
480 mg/l
24 hours