- Natural product: Guggul (Commiphora mukul)
- Associated study: Guggul oleo-gum resin extract Nuclear Receptor Induction study - Ole Miss
In Vitro Nuclear Receptor Induction Experiment
Guggul - In Vitro Nuclear Receptor Induction PXR Experiment - 3
Induction was detected. Cutoff used —
An activation of 2-folds or higher.
- Pregnane X receptor (PXR)
Cell system PXR-transfected hepatic cells
Results
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
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Experimental Conditions
Luciferase activity (Reporter gene assay)
50,000 cells/well in 96-well plates
No
6.7 µg/mL
24 hrs for PXR induction