Weak Inhibition of Speciogynine for CYP2C9 CSV JSON

In Vitro Enzyme Inhibition Experiment

Weak Inhibition of Speciogynine for CYP2C9

Negligible Inhibition was detected.  Cutoff used —

IC50 = 45 μM

diclofenac 1124300

speciogynine

4'-hydroxydiclofenac

  • CYP2C9 4309227

Cell fraction Pooled human liver microsomes -7999662

Results

% result estimated from Figure S2 at around 30 µM

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.1 mg/ml

200 µL

15 min

NADPH

6 µM

0 - 100 µM

Control Experiment