- Natural product: Shrubby sophora (Sophora flavescens)
- Associated study: Chinese Herbal Medicine Sophora Flavescens Activates PXR
In Vitro Nuclear Receptor Induction Experiment
Sophoranol - Effect on PXR Activation Experiment - 6
Non-induction was detected. Cutoff used —
≥ positive control (rifampicin)
- Pregnane X receptor (PXR)
Cell system PXR-transfected hepatic cells
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
Luciferase activity (Reporter gene assay)
2x10^5 cells/ml (100 μl in each well)
10 μM
24 hours