Coptis - In Vitro Nuclear Receptor Induction PXR Experiment - 1 CSV JSON

In Vitro Nuclear Receptor Induction Experiment

Coptis - In Vitro Nuclear Receptor Induction PXR Experiment - 1

Induction was detected.  Cutoff used —

An activation of 2-folds or higher. 

coptis extract

  • Pregnane X receptor (PXR)

Cell system PXR-transfected hepatic cells

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates
coptis extract5.04 ± 0.18-foldChange from vehicle control
Mean ± SD (arithmetic)		Test
P-value:
P < 0.05
2

Experimental Conditions

Luciferase activity (Reporter gene assay)

50,000 cells/well in 96-well plates

No

60 µg/mL

24 hrs for PXR induction