Inhibition of CYP1A2 by G. inflata Licorice extract CSV JSON

In Vitro Enzyme Inhibition Experiment

Inhibition of CYP1A2 by G. inflata Licorice extract

Inhibition was detected.  Cutoff used —

> 100 µg/ml

phenacetin 19033710

acetaminophen 1125315

  • CYP1A2 4312402

Cell fraction Pooled human liver microsomes -7999662

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.2 mg/mL

10 min

NADPH

100 µM

11 concentrations from 0.005–250 μg/mL