- Natural product: Shrubby sophora (Sophora flavescens)
- Associated study: Chinese Herbal Medicine Sophora Flavescens Activates PXR
In Vitro Nuclear Receptor Induction Experiment
Matrine - Effect on PXR Activation Experiment - 3
Non-induction was detected. Cutoff used —
≥ positive control (rifampicin)
- Pregnane X receptor (PXR)
Cell system PXR-transfected hepatic cells
Results
Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
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Experimental Conditions
Luciferase activity (Reporter gene assay)
2x10^5 cells/ml (100 μl in each well)
10 μM
24 hours