Evaluation of Time-Dependent CES1 Inhibition by CBN (30 min) CSV JSON

In Vitro Enzyme Inhibition Experiment

Evaluation of Time-Dependent CES1 Inhibition by CBN (30 min)

Inhibition was detected.  Cutoff used —

Not provided

oseltamivir phosphate

cannabinol

oseltamivir acid

  • CES1

Cell fraction Human kidney S9 fraction

Results

IC50 pre-incubation 0 min (A) = 4.03 µM
IC50 pre-incubation 30 min (B) = 8.51 µM
B/A = 2.11

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

20 µg/mL

Commercially available

100 µL

15 min

1 mM

30 min

30 min

0 - 50 µg/mL