Weak Inhibition of 7-hydroxymitragynine for CYP1A2 CSV JSON

In Vitro Enzyme Inhibition Experiment

Weak Inhibition of 7-hydroxymitragynine for CYP1A2

Negligible Inhibition was detected.  Cutoff used —

IC50 = 45 μM

phenacetin 19033710

7-hydroxymitragynine

acetaminophen 1125315

  • CYP1A2 4312402

Cell fraction Pooled human liver microsomes -7999662

Results

% result estimated from Figure S4 at around 100 µM

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.1 mg/ml

200 µL

15 min

NADPH

40 µM

1 - 100 µM

Control Experiment