2C9 Inhibition by (+) Hydrastine CSV JSON

In Vitro Enzyme Inhibition Experiment

2C9 Inhibition by (+) Hydrastine

Inhibition was detected.  Cutoff used — not specified

diclofenac 1124300

hydrastine

4'-hydroxydiclofenac

  • CYP2C9 4309227

Cell fraction Pooled human liver microsomes -7999662

Results

Fig 4c at 1000 μM

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.5 mg/mL

Commercially available

30 min

NADPH

100 μ􏱂M

No NADPH with precipitant

10, 100, and 1000 μ􏱂M