Amprenavir P-gp Inhibition CSV JSON

In Vitro Transporter Kinetics Experiment

Amprenavir P-gp Inhibition

Transport Activity was detected.  Cutoff used — not specified

berberine 19012197

  • P-gp (ABCB1)

Transfected / siRNA knock-out / injected cells MDCK transfected cells

Results

Figure 5b - reported value above is for 25 μM of Amprenavir vs control and is significant p< 0.05

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

Amprenavir concentration tested: 5, 15, and 25  μM

Cell Culture Conditions

5

Assay Conditions

4 h

37 deg C

5 μM