Percent inhibition of CYP2E1 by epicatechin gallate CSV JSON

In Vitro Enzyme Inhibition Experiment

Percent inhibition of CYP2E1 by epicatechin gallate

Inhibition was detected.  Cutoff used — not provided

4-nitrophenol

epicatechin gallate

4-nitrocatechol

  • CYP2E1 4173608

Recombinant expression system Not available
Cytochrome B5 Not available

Results

Percent inhibition at 100 µM as estimated from Fig. 3 is presented.

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

Experiments were conducted using TA1538 cell membrane fractions expressing P450 reductase and individual CYP isoforms.

CYP: 20 pmol/mL

In-house preparation

0.5 mL

30 min at pH 6.8

NADPH regenerating system

Not available

Not available

100 µM

0-100 µM