CBD Effect on Stiripentol Concentrations CSV JSON

In Vivo Interaction Study

CBD Effect on Stiripentol Concentrations

Increased systemic exposure was detected.

stiripentol

cannabidiol (cbd)

Study GWEP1543

Results

When CBD was combined with stiripentol there was a minor increase in Cmax and AUCtau; 1.28 and 1.55-fold, respectively.

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

Fixed-sequence
Parallel
Multiple dosing

Population

Females
Healthy volunteers
Males

12

Arm 1, Group 3

Drug or Natural Product Administration

Object Administration — stiripentol

Oral

Not stated

1500 mg

750 mg BID

14 days

Precipitant Administration — cannabidiol (cbd)

Oral

Solution

1500 mg

750 mg BID

14 days

Natural Product Characteristics

Not specified