- Natural product: Cannabis (Cannabis sativa)
- Associated study: In Vitro Inhibition of Carboxylesterase 1 by Major Cannabinoids and Selected Metabolites
In Vitro Enzyme Inhibition Experiment
Inhibition of CES1 by THC
Inhibition was detected. Cutoff used —
90% inhibition
- CES1
Cell fraction Human kidney S9 fraction
Results
Table 2
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
20 microG/ml
Commercially available
100 µL
15 min
0, 100, 500, 1000, 2500, 5000 µM
0 - 10 µg/mL