Valproic Acid Effect on CBD CSV JSON

In Vivo Interaction Study

Valproic Acid Effect on CBD

Decreased systemic exposure was detected.

cannabidiol (cbd)

valproic acid

Study GWEP1543

Results

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

Fixed-sequence
Parallel
Multiple dosing

Population

Females
Healthy volunteers
Males

14

Arm 2, Group 6

Drug or Natural Product Administration

Object Administration — cannabidiol (cbd)

Oral

Solution

1500 mg

750 mg BID

9 days

Precipitant Administration — valproic acid

Oral

Not specified

1000 mg

500 mg BID

9 days

Natural Product Characteristics

Not specified