3A4 Inhibition by (-) Hydrastine CSV JSON

3A4 Inhibition by (-) Hydrastine

Object compound

Precipitant

Object metabolite investigated

Enzymes involved in metabolite pathway

Test system used

Cell fraction Pooled human liver microsomes -7999662

fig 4a at 1000 μM

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

Protein concentration

0.2 mg/mL

Test system preparation

Commercially available

Incubation time

15 min

Co-factors

NADPH

Object concentrations tested

200 μ􏱂M

Precipitant pre-incubation condition

No NADPH with precipitant

Precipitant concentrations tested

10, 100, and 1000 μ􏱂M

NOTE