Percent inhibition of CYP2A6 by epicatechin gallate CSV JSON

In Vitro Enzyme Inhibition Experiment

Percent inhibition of CYP2A6 by epicatechin gallate

Inhibition was detected.  Cutoff used — not provided

coumarin 19008106

epicatechin gallate

7-hydroxycoumarin

  • CYP2A6 4309826

Recombinant expression system Not available
Cytochrome B5 Not available

Results

Percent inhibition at 100 µM as estimated from Fig. 3 is presented.

Sample Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

Experiments were conducted using TA1538 cell membrane fractions expressing P450 reductase and individual CYP isoforms.

CYP: 20 pmol/mL

In-house preparation

0.5 mL

15 min

NADPH regenerating system

Not available

Not available

1 µM

0-100 µM