Inhibition of UGT1A6 by Epigallocatechin Gallate CSV JSON

In Vitro Enzyme Inhibition Experiment

Inhibition of UGT1A6 by Epigallocatechin Gallate

Inhibition was detected.  Cutoff used — >20% inhibiton vs. control

serotonin

epigallocatechin gallate 19058494

serotonin glucuronide

  • UGT1A6

Cell fraction Pooled human liver microsomes -7999662

Results

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

0.5 mg/mL

Commercially available

100 ┬ÁL

60 min

UDPGA

8 mM

250 mg in 53, 5.3, and 0.53 L