NaPDI | Compound details

Need public description.

Natural products containing this compound

Green Tea (Camellia sinensis)

Enantiomer of compound
None listed

Compound has enantiomers

(-)-epigallocatechin gallate

Metabolite of compounds
None listed

Compound has metabolites
None listed

ID	Subject of Study	Study Name	Name	Type	Overall Effect	Enzymes	Transporters	Object	Object Metabolite	Precipitant
NPDI-URZBxQ	Green Tea (Camellia sinensis)	Inhibitory effects of commonly used herbal extracts on UDP-glucuronosyltransferase 1A4, 1A6, and 1A9 enzyme activities	Inhibition of UGT1A4 by Epigallocatechin Gallate	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	UGT1A4		trifluoperazine	trifluoperazine glucuronide	epigallocatechin gallate
NPDI-Cuu5WA	Green Tea (Camellia sinensis)	Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450		In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP3A4		midazolam	1'-hydroxymidazolam	epigallocatechin gallate
NPDI-Dg01cQ	Green Tea (Camellia sinensis)	Inhibitory effects of commonly used herbal extracts on UDP-glucuronosyltransferase 1A4, 1A6, and 1A9 enzyme activities	Inhibition of UGT1A6 by Epigallocatechin Gallate	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	UGT1A6		serotonin	serotonin glucuronide	epigallocatechin gallate
NPDI-mzhpNw	Green Tea (Camellia sinensis)	Inhibitory effects of commonly used herbal extracts on UDP-glucuronosyltransferase 1A4, 1A6, and 1A9 enzyme activities	Inhibition of UGT1A9 by Epigallocatechin Gallate	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	UGT1A9		mycophenolic acid	mycophenolic acid 7-o-glucuronide	epigallocatechin gallate
NPDI-r41Z9w	Green Tea (Camellia sinensis)	Inhibitory effects of commonly used herbal extracts on UGT1A1 enzyme activity.	EGCG inhibition of UGT1A1	In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	UGT1A1		17-beta-estradiol	17-beta-estradiol-3-o-glucuronide	epigallocatechin gallate
NPDI-p7eJTA	Green Tea (Camellia sinensis)	Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450		In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP1A2		7-ethoxyresorufin	resorufin	epigallocatechin gallate
NPDI-vyz23w	Green Tea (Camellia sinensis)	Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450		In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP1A1		7-ethoxycoumarin	coumarin	epigallocatechin gallate
NPDI-q6-gZQ	Green Tea (Camellia sinensis)	Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450		In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2A6		coumarin	7-hydroxycoumarin	epigallocatechin gallate
NPDI-_5Ix4Q	Green Tea (Camellia sinensis)	Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450		In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2E1		4-nitrophenol	4-nitrocatechol	epigallocatechin gallate
NPDI-38xlLg	Green Tea (Camellia sinensis)	Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450		In Vitro Enzyme Inhibition	positive — In Vitro Enzyme Inhibition	CYP2C9		diclofenac	4'-hydroxydiclofenac	epigallocatechin gallate

ID	Subject of Study	Name
NPDI-zg6Npw	Green Tea (Camellia sinensis)	Inhibitory effects of commonly used herbal extracts on UDP-glucuronosyltransferase 1A4, 1A6, and 1A9 enzyme activities
NPDI-dCfz1g	Green Tea (Camellia sinensis)	Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450
NPDI-S1YNJQ	Green Tea (Camellia sinensis)	Inhibitory effects of commonly used herbal extracts on UGT1A1 enzyme activity.

Compound information from external resources

Resource	Identifier
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