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  • Green tea (Camellia sinensis)

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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-mzhpNw Green tea (Camellia sinensis) Inhibitory effects of commonly used herbal extracts on UDP-glucuronosyltransferase 1A4, 1A6, and 1A9 enzyme activities Inhibition of UGT1A9 by Epigallocatechin Gallate In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT1A9
mycophenolic acid mycophenolic acid 7-o-glucuronide epigallocatechin gallate
NPDI-Dg01cQ Green tea (Camellia sinensis) Inhibitory effects of commonly used herbal extracts on UDP-glucuronosyltransferase 1A4, 1A6, and 1A9 enzyme activities Inhibition of UGT1A6 by Epigallocatechin Gallate In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT1A6
serotonin serotonin glucuronide epigallocatechin gallate
NPDI-_5Ix4Q Green tea (Camellia sinensis) Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2E1
4-nitrophenol 4-nitrocatechol epigallocatechin gallate
NPDI-q6-gZQ Green tea (Camellia sinensis) Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2A6
coumarin 7-hydroxycoumarin epigallocatechin gallate
NPDI-vyz23w Green tea (Camellia sinensis) Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxycoumarin coumarin epigallocatechin gallate
NPDI-URZBxQ Green tea (Camellia sinensis) Inhibitory effects of commonly used herbal extracts on UDP-glucuronosyltransferase 1A4, 1A6, and 1A9 enzyme activities Inhibition of UGT1A4 by Epigallocatechin Gallate In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT1A4
trifluoperazine trifluoperazine glucuronide epigallocatechin gallate
NPDI-p7eJTA Green tea (Camellia sinensis) Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A2
7-ethoxyresorufin resorufin epigallocatechin gallate
NPDI-r41Z9w Green tea (Camellia sinensis) Inhibitory effects of commonly used herbal extracts on UGT1A1 enzyme activity. EGCG inhibition of UGT1A1 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • UGT1A1
17-beta-estradiol 17-beta-estradiol-3-o-glucuronide epigallocatechin gallate
NPDI-Cuu5WA Green tea (Camellia sinensis) Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP3A4
midazolam 1'-hydroxymidazolam epigallocatechin gallate
NPDI-38xlLg Green tea (Camellia sinensis) Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP2C9
diclofenac 4'-hydroxydiclofenac epigallocatechin gallate

Compound information from external resources

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