In Vitro Enzyme Inhibition Experiment
Inhibition of UGT1A9 by Epigallocatechin Gallate
Inhibition was detected. Cutoff used — >20% inhibiton vs. control
Cell fraction Pooled human liver microsomes -7999662
Percent inhibition was estimated from Fig. 1. Epigallocaetchin gallate at 250 mg in 53 and 5.3 L did not inhibit UGT1A9-mediated mycophenolic acid 7-O-glucuronide formation.
|Compound measured||Measurement||Value||Study sequence||Additional information||N replicates|
250 mg in 0.53 L