- Natural product: Green tea (Camellia sinensis)
- Associated study: Inhibitory effects of commonly used herbal extracts on UDP-glucuronosyltransferase 1A4, 1A6, and 1A9 enzyme activities
In Vitro Enzyme Inhibition Experiment
Inhibition of UGT1A4 by Epigallocatechin Gallate
Inhibition was detected. Cutoff used — >20% inhibiton vs. control
- UGT1A4
Cell fraction Pooled human liver microsomes -7999662
Results
| Sample | Compound measured | Value | Measurement | Study sequence | Additional information | N replicates |
|---|
Experimental Conditions
0.1 mg/mL
Commercially available
20 min
UDPGA
Not available
Not available
60 µM
0.05-1000 µg/mL (estimated from Fig. 2)