Experiment #NPDI-vyz23w CSV JSON

In Vitro Enzyme Inhibition Experiment

Inhibition was detected.  Cutoff used — N/A

7-ethoxycoumarin

epigallocatechin gallate 19058494

coumarin 19008106

  • CYP1A1 4173297

Recombinant expression system Not available
Cytochrome B5 Not available

Results

The apparent Ki value is presented in the table.

Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

Experiments were conducted using TA1538 cell membrane fractions expressing P450 reductase and individual CYP isoforms.

CYP: 20 pmol/mL

In-house preparation

0.5 mL

15 min

NADPH regenerating system

Not available

Not available

10 µM

50 µM