resorufin

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Compound information managed by NaPDI


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ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-OFFj8Q Goldenseal (Hydrastis canadensis) An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures 3A4 Inhibition by Berberine In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP3A4
7-ethoxyresorufin resorufin berberine
NPDI-5sDXyA Goldenseal (Hydrastis canadensis) The Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated Inhibition CYP1A1 preincubation with NADPH In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin berberine
NPDI-ArhlIA Green tea (Camellia sinensis) Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450 Percent inhibition of CYP1A2 by epicatechin gallate In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A2
7-ethoxyresorufin resorufin epicatechin gallate
NPDI-4tAywg Cannabis (Cannabis sativa) Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 enzymes 1A1: THC In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin delta-9-tetrahydrocannabinol
NPDI-bxWjqg Cannabis (Cannabis sativa) Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 enzymes HLMs: CBD In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabidiol
NPDI-DQGnJw Cannabis (Cannabis sativa) Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 enzymes HLMs: THC In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin delta-9-tetrahydrocannabinol
NPDI-wnmeug Cannabis (Cannabis sativa) Characterization of the structural determinants required for potent mechanism-based inhibition of human cytochrome P450 1A1 by cannabidiol Cannabidivarin In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabidivarin
NPDI-XKoD2A Cannabis (Cannabis sativa) Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 enzymes HLMs: CBN In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabinol
NPDI-DqfMEw Cannabis (Cannabis sativa) Characterization of the structural determinants required for potent mechanism-based inhibition of human cytochrome P450 1A1 by cannabidiol Cannbidiol-2'-monomethyl ether In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabidiol-2'-monomethyl ether
NPDI-F-0XWg Cannabis (Cannabis sativa) Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 enzymes 1A2: THC In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A2
7-ethoxyresorufin resorufin delta-9-tetrahydrocannabinol
NPDI-BfJ7dA Cannabis (Cannabis sativa) Structural requirements for potent direct inhibition of human cytochrome P450 1A1 by cannabidiol: role of pentylresorcinol moiety. Cannabidiol In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabidiol
NPDI-jYDUsw Cannabis (Cannabis sativa) Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 enzymes 1A1: CBD In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabidiol
NPDI-FompNA Cannabis (Cannabis sativa) Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 enzymes 1A2: CBD In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A2
7-ethoxyresorufin resorufin cannabidiol
NPDI-ZdbG7w Goldenseal (Hydrastis canadensis) The Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated Inhibition CYP1A2 preincubation w/o NADPH In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP1A2
7-ethoxyresorufin resorufin berberine
NPDI-iJRQWg Cannabis (Cannabis sativa) Structural requirements for potent direct inhibition of human cytochrome P450 1A1 by cannabidiol: role of pentylresorcinol moiety. THC In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin delta-9-tetrahydrocannabinol
NPDI-pQrX0g Cannabis (Cannabis sativa) Characterization of the structural determinants required for potent mechanism-based inhibition of human cytochrome P450 1A1 by cannabidiol CBD-dimethyl ether In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabidiol-dimethyl ether
NPDI-E6xHTA Cannabis (Cannabis sativa) Structural requirements for potent direct inhibition of human cytochrome P450 1A1 by cannabidiol: role of pentylresorcinol moiety. Cannabidiol-2'-monomethyl ether In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabidiol-2'-monomethyl ether
NPDI-p7eJTA Green tea (Camellia sinensis) Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450 In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A2
7-ethoxyresorufin resorufin epigallocatechin gallate
NPDI-b6F8pQ Cannabis (Cannabis sativa) Characterization of the structural determinants required for potent mechanism-based inhibition of human cytochrome P450 1A1 by cannabidiol Cannabidiol In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabidiol
NPDI-ZmjyHw Cannabis (Cannabis sativa) Structural requirements for potent direct inhibition of human cytochrome P450 1A1 by cannabidiol: role of pentylresorcinol moiety. Cannabidvarin In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabidivarin
NPDI-jjh4MA Goldenseal (Hydrastis canadensis) The Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated Inhibition 1A2 pre-incubation with NADPH In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP1A2
7-ethoxyresorufin resorufin berberine
NPDI-RC8Kxw Cannabis (Cannabis sativa) Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 enzymes 1A2: CBN In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A2
7-ethoxyresorufin resorufin cannabinol
NPDI-NAiMNw Goldenseal (Hydrastis canadensis) The Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated Inhibition Pre-incubation w/o NADPH In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin berberine
NPDI-9ju4Lw Cannabis (Cannabis sativa) Structural requirements for potent direct inhibition of human cytochrome P450 1A1 by cannabidiol: role of pentylresorcinol moiety. Cannabidiol-2',6'-dimethyl ether In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabidiol-dimethyl ether
NPDI-v65nxg Cannabis (Cannabis sativa) Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoform-selective and potent inhibitors of human CYP1 enzymes 1A1: CBN In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabinol