In Vitro Enzyme Inhibition Experiment

1A2: CBN

Inhibition was detected.  Cutoff used — Not specified

7-ethoxyresorufin -7999995

cannabinol (CBN)

resorufin -7999853

  • CYP1A2 4312402

Recombinant expression system Baculovirus-insect cells
Cytochrome B5 No

Results

Tables 2 and 3
IC50 at 20 min

Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

96-well

60 fmol

Commercially available

200 μL

30 min

NADPH

150 nM

5 min

No NADPH with precipitant

0.025-25 μM