In Vitro Enzyme Inhibition Experiment

1A1: CBD

Inhibition was detected.  Cutoff used — Not specified

7-ethoxyresorufin -7999995

cannabidiol

resorufin -7999853

  • CYP1A1 4173297

Recombinant expression system Baculovirus-insect cells
Cytochrome B5 No

Results

Tables 2, 3, and 4. 
IC50 at 20 min.
Fig 4. % inhibition estimated with 0.625 μM
Fig 5. With NADPH at 9 min

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

96-well

10 fmol

Commercially available

200 μL

30 min

NADPH

150 nM

5 min

No NADPH with precipitant

0.025-25 μM