In Vitro Enzyme Inhibition Experiment

Cannabidivarin

Inhibition was detected.  Cutoff used — Not specified

7-ethoxyresorufin -7999995

cannabidivarin

resorufin -7999853

  • CYP1A1 4173297

Recombinant expression system Baculovirus-insect cells
Cytochrome B5 Not available

Results

%inhibition estimated from Fig 2 at 20 min, ~0.5 μM CBDV.
IC50 at 0 min (table 1).
IC50 at 20 min 0.0677
Kinact/KI converted from /min/mmol to /min/μM (table 2).
All other values from Table 2.

Compound measured Measurement Value Study sequence Additional information N replicates

Experimental Conditions

Commercially available

200 µL

30 min

NADPH

20 µL

180 µL

5 min

NADPH with precipitant