3A4 Inhibition by Berberine CSV JSON

3A4 Inhibition by Berberine

Object compound

Precipitant

Object metabolite investigated

Enzymes involved in metabolite pathway

Test system used

Recombinant expression system Baculovirus-insect cells
Cytochrome B5 Not available

IC50 from Table 2: converted from mM (5.72 mM)
% inhibition from Table 1 (percent of full strength)
p (1 tail)

Sample	Compound measured	Value	Measurement	Study sequence	Additional information	N replicates

Protein concentration

30 μL/mL

Incubation volume

200 μL

Incubation time

1 h

Object concentrations tested

1.5 mg/mL

Precipitant pre-incubation time

10 min

Precipitant pre-incubation condition

NADPH with no precipitant

Dilution factor

3 dilutions

Precipitant concentrations tested

62.5 μg/mL

NOTE