In Vitro Enzyme Inhibition Experiment

HLMs: CBD

Inhibition was detected.  Cutoff used — Not specified

7-ethoxyresorufin -7999995

cannabidiol

resorufin -7999853

  • CYP1A1 4173297

Cell fraction Pooled human liver microsomes -7999662

Results

Tables 2 and 3.
IC50 at 20 min

Sample Compound measured Value Measurement Study sequence Additional information N replicates

Experimental Conditions

96-well

5 μg

Commercially available

200 μL

30 min

NADPH

150 nM

5 min

No NADPH with precipitant

0.025-25 μM