CBD derivative


None listed

None listed

None listed

None listed
ID Subject of Study Study Name Name Type Overall Effect Enzymes Transporters Object Object Metabolite Precipitant
NPDI-9ju4Lw Cannabis (Cannabis sativa) Structural requirements for potent direct inhibition of human cytochrome P450 1A1 by cannabidiol: role of pentylresorcinol moiety. Cannabidiol-2',6'-dimethyl ether In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabidiol-dimethyl ether
NPDI-pQrX0g Cannabis (Cannabis sativa) Characterization of the structural determinants required for potent mechanism-based inhibition of human cytochrome P450 1A1 by cannabidiol CBD-dimethyl ether In Vitro Enzyme Inhibition positive — In Vitro Enzyme Inhibition
  • CYP1A1
7-ethoxyresorufin resorufin cannabidiol-dimethyl ether
NPDI-y29wsw Cannabis (Cannabis sativa) Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6. Recombinant: CBDM-AMMC In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2D6
3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-methoxy-4-methylcoumarin 3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-hydroxy-4-methylcoumarin cannabidiol-dimethyl ether
NPDI-F3DjaQ Cannabis (Cannabis sativa) Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6. Recombinant: CBDD-AMMC In Vitro Enzyme Inhibition negative — In Vitro Enzyme Negligible Inhibition
  • CYP2D6
3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-methoxy-4-methylcoumarin 3-[2-(n,n-diethyl-n-methylammonium)ethyl]-7-hydroxy-4-methylcoumarin cannabidiol-dimethyl ether

Compound information from external resources

Resource Identifier
Google search UYBGHBAVRNATET-VQTJNVASSA-N